منابع مشابه
RFC 4445 A Proposed Media
Status of This Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. This RFC is not a candidate for any level of Internet Standard. There are IETF standards which are highly applicable to the space defined by this document as its applicability, in particular, RFCs 3393 and 3611, and there is...
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The present study was aimed at characterizing the mechanisms by which neurotensin (NT) is acting within the ventral midbrain to induce a psychostimulant-like effect. In a first experiment, we determine which subtype(s) of NT receptors is/are involved in the reward-inducing effect of ventral midbrain microinjection of NT using the conditioned place-preference (CPP) paradigm. In a second study, w...
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To understand the effect of the replacement of Tyr residue at position 1 in opioid peptides by 2,6-dimethyl-Tyr (Dmt) on the biological property, chiral (D or L) Dmt1 analogs of Leu-enkephalin (Enk) and Tyr-D-Arg-Phe-beta Ala-NH2 (YRFB) were synthesized and their enzymatic stabilities, in vitro bioactivities and receptor binding affinities compared with those of parent peptides. [L-Dmt1]Enk (1)...
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A new method bused on MLE-OED is proposed for unsupervised image segmentation of multiple objects which have fuzzy edges. It adjusts the parameters of a mixture of Gaussian distributions via minimizing a new loss function proposed to implement image segmentation bused on the image’s local spatial information and global intensity distribution properties . The loss function consists of two terms:...
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DTD (D-Tyr-tRNA(Tyr) deacylase) is known to be able to deacylate D-aminoacyl-tRNAs into free D-amino acids and tRNAs and therefore contributes to cellular resistance against D-amino acids in Escherichia coli and yeast. We have found that h-DTD (human DTD) is enriched in the nuclear envelope region of mammalian cells. Treatment of HeLa cells with D-Tyr resulted in nuclear accumulation of tRNA(Ty...
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ژورنال
عنوان ژورنال: The Classical Review
سال: 1892
ISSN: 0009-840X,1464-3561
DOI: 10.1017/s0009840x00185233